J 1

Consider the Wright-Fisher model for two alleles A and a with N= 4 individuals and initial allele frequency fA(0) = 0.5

(a) What is the probability that the A allele becomes fixed in generation 1?

(b) What is the probability that the A allele eventually becomes fixed?

(c) What is the expected allele frequency in generation 100?

(d) Would any of your answers to (a), (b) and (c) change if the population was modelled with the Moran model instead of the Wright-Fisher model, with the same population size N and the same initial allele frequency? If so, recalculate them. If not, explain why not.