Question: mass-transfer problem The patch for delivering the drug through the skin contains 0.06 M of drug solution in a capsule with a thickness of 2

mass-transfer problem

The patch for delivering the drug through the skin contains 0.06 M of drug solution in a capsule with a thickness of 2 mm and a diameter of 3 cm. Before attaching this, a 250 m thick polymer membrane was placed between the capsule and the skin. The diffusion coefficient of the drug in the solution is 5.4 x 10^-6 cm²/sec, and the diffusion coefficient in the polymer is 1.8 x 10^-7 cm²/sec. The equilibrium concentration in the polymer phase is 0.6 times the equilibrium concentration in the solution. It is assumed that the drug is absorbed quickly by the skin, and the concentration at the polymer-skin interface is zero. (a) How much is the drug in the capsule absorbed in the first 2 hours? (b) When does the discharge rate of the drug become half the initial rate? How many moles have been discharged by that time? (c) Can you suggest a way to ensure that the drug is discharged at a nearly constant rate?

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock blur-text-image

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Chemical Engineering Questions!

I asked this question, but the answer to (b) was cut off in the middle. I want a more detailed explanation of (b). The patch for delivering the drug through the skin contains 0.06M of drug solution...

The patch for delivering the drug through the skin has a thickness of 2 mm and A 0.06 M drug solution is contained in a capsule with a diameter of 3 cm. paste this A 250 m thick polymer membrane was...

I Need help with D, E and F! Please (30 points) A transdermal patch for drug delivery contains a 0.05M solution of the drug in a capsule 2mm thick and 3cm in diameter. This patch is applied by first...

A transdermal patch for drug delivery contains a 0.06M solution of the drug in a capsule 2 mm thick and 3.0 cm in diameter. Just before application, a 250-m polymer film is placed between the capsule...

Declan Dixon, director of marketing for Warner-Lambert Ireland (WLI), examined two very different sales forecasts as he considered the upcoming launch of Niconil, scheduled for January 1990. Niconil...

mass-transfer problem Water saturated with air at 20C passes through a hydrophobic-hollow fiber(membrane) at a speed of 50 cm/s. The hollow fiber is 1 m long and has an inner diameter of 500 m, and a...

Problem 1: A wetted-wall column is sometimes used to strip volatile organic solutes such as TCE from an aqueous solution. To estimate the gas film coefficient (kG) for a wetted-wall column, a...

For mass transfer across the hollow-fiber membrane contactors described in Example 2.14, the overall mass-transfer coefficient based on the liquid concentration, $K_{L}$, is given by (Yang and...

Case Study: Engineering project Management Strategic Planning Etisalat employs strategic plan in its operations concerning product development and market control. Currently, the company provides its...

Introduction In this task, you will design the capstone project approved by your instructor. You will write a report about the security problem you identified in Task 1 and compile the information...

1. Paige cultured 100,000 paramecium (unicellular). Ten days later, the population grew to 500,000 paramecium cells. Calculate the intrinsic rate of increase (r) for her population. (Show all...

dy Given y = x (3x + 5x 5). Find dx x=3 dy 1123 dx \x=3 Submit Answer You have entered that answer before Incorrect. Tries 2/99 Previous Tries -3969

Arden Inc. prepares its variable overhead performance report on the basis of the actual direct labour - hours for the period. Data from the most recent fiscal year, which ended on March 3 1 , are...

The following is the sales budget for Shleifer, Inc., for the first quarter 2020 Credit sales are collected as follows: 65 percent in the month of the sale. 20 percent in the month after the sale. 15...

Continuous cultural-general training as part of a management development process which encourages flexibility across cultures may be more effective than culture-specific training on a one-off basis.

Adequate research and risk taking regarding women in difficult cultures should be undertaken. Evidence should be produced if the risks are seen as too high.

When expatriates are drawn from different countries, career expectations may be different as well as expectations of the way careers should be managed. The level of intervention required by the...