Patient Package Inserts A patient package insert (PPI) is FDA-approved labeling written in patient-friendly language that explains the uses, risks, and precautions related to a particular drug.' These are supplied by the manufacturer with the product and must be dispensed with the drug both on new prescriptions and refills. These laws don't just apply to retail pharmacies; they apply to any person who dispenses drugs, including institutions and practitioners dispensing prescriptions from their office. In institutions, including long-term care facilities and hospitals, PPIs are usually given to patients with the first dose of medication and at least every 30 days thereafter. The only drugs that PPIs are currently required for are estrogens and oral contraceptives; however, other drugs may come with PPIs if a manufacturer believes having one would benefit the patient. 1-3.7.26-28