please answer all parts and explain

QUESTION THREE (SO MARKS] Answer ALL parts (a) to (c) (a) Drugs are applied topically for a variety of effects including antiseptics, antifungals, anti- inflammatory agents, as well as skin emollients for protective features. Ointments, creams, pastes and gels are all semi-solid preparations. Outline the different methods of manufacture used and give a brief comparison of the formulations. (20 marks] (b) The majority of drugs are weak organic acids or bases. For example Aspirin is a weak acid and the oplate pain killer, Morphine, Is a weak base. Describe how the above statement influences the drug formulations. Give specific examples of buffers and their role in drug design. (8 marks] (c) Extemporaneously prepared medicine must be appropriately labelled in accordance with the requirements set out in the Medicinal Products (Prescription and Control of Supply Regulations 2003 (as amended) and in addition must meet all requirements set out in the Council of Europe Resolution. List these requirements and write a brief note on thelr rationale. (22 marks]