Question: The process development group wants to evaluate 2 new formulations A and B for the Wonderdrug tablets to see if their dissolution (% of API

The process development group wants to evaluate 2 new formulations A and B for the Wonderdrug tablets to see if their dissolution (% of API dissolved in 30 minutes) is comparable or different from each other and from the current (reference) formulation R. To do the comparison we collected 12 tablets from each of the three formulations (A, B, R). Our lab has two dissolution apparatuses DA-1 and DA-2, each capable of analyzing 6 tablets at a time. Two chemists Peter and Jane - are available to conduct the study. Develop (manually) a table for conducting the experiment: who should test each of the 36 tablets, in which apparatus, and in what order. Explain why you proposed that plan. Explain how you would conduct the comparison of those formulations with respect to dissolution after collecting the experimental data and what your conclusions may look like after the analysis.

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Students Have Also Explored These Related Chemical Engineering Questions!