The structural formulas and relevant pKa values for the four components of an Excedrin tablet are...
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The structural formulas and relevant pKa values for the four components of an Excedrin tablet are shown. (The protonated form of the boxed group is shown.) A. Predict the migration order in capillary zone electrophoresis with a 20 mM borate run buffer at pH = 9.3. (Hint: First figure out charges on the species.) CA-] PH = pka + log CHAJ ĐX 3.5 OH HO DK - 9.9 Acetaminophen Aspirin (acetyl salicylic acid) pK, = 3.0 OH OH ĐK = 13.4 ĐK, = 10.6 CH, salicylic acid caffeine B. What could you do experimentally to confirm your predicted elution order? The structural formulas and relevant pKa values for the four components of an Excedrin tablet are shown. (The protonated form of the boxed group is shown.) A. Predict the migration order in capillary zone electrophoresis with a 20 mM borate run buffer at pH = 9.3. (Hint: First figure out charges on the species.) CA-] PH = pka + log CHAJ ĐX 3.5 OH HO DK - 9.9 Acetaminophen Aspirin (acetyl salicylic acid) pK, = 3.0 OH OH ĐK = 13.4 ĐK, = 10.6 CH, salicylic acid caffeine B. What could you do experimentally to confirm your predicted elution order?
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B To confirm predicted elution order we have to use capillary zone electrophoresis technique which i... View the full answer
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