Question: We have studied the controlled drug delivery problem in hemispherical plant matrix in Homework 4. We want to analyze this process for alternative matrix shapes:

 We have studied the controlled drug delivery problem in hemispherical plant

We have studied the controlled drug delivery problem in hemispherical plant matrix in Homework 4. We want to analyze this process for alternative matrix shapes: a slab of thickness 2L (Flg. 1 ), and a sphere of radius R (Fig. 2). The shaded area is the solid dispersion and other regions are solution. The position of the solution-dispersion interface is f(t)(f(0)=0). The drug concentration in the dispersion is CS, the aqueous concentration at the lnterface is C0 and the effective diffusivity of the drug through the water-filled part of the matrix is D. It is assumed that the concentrations at x=0 and r=R are negligible and C0/Cs&1. [15pt] (a) find the lifetime and the rate of drug release (mol/s) as a function of time of the siab shape [15pt] (b) find the lifetime and the rate of drug release (mol/s) as a function of time of the spherical device. shape device

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