With python 3:

1). Append a new variable ( Amount= UnitPrice* Units)

2). Average unit price for each region. Use the groupby()method

3). Average unit price for each region. Use the pivot_table()method.

Date	Region	Item	UnitPrice	Units
14-Jul-18	East	Pen Set	3.85	71
16-Jul-18	East	Binder	14.00	31
22-Jul-18	Central	Pen Set	10.50	46
25-Jul-18	West	Binder	22.00	44