Question: You calculate the stratum specific ORs for the 3rd variable smoking in the relationship between alcohol consumption and kidney disease. The crude OR is 1.78.

You calculate the stratum specific ORs for the 3rd variable smoking in the relationship between alcohol consumption and kidney disease. The crude OR is 1.78. The OR for the relationship between alcohol consumption and kidney disease among smokers is 3.47 and the OR for the relationship between alcohol consumption and kidney disease among non-smokers is 1.15. Is it appropriate to calculate Mantel-Haenszel odds ratio? If it is not appropriate to calculate the Mantel-Haenszel odds ratio in this situation, what would you report?

A.

Confounding is present, it is appropriate to report the MH OR

b

Confounding is not present, it is not appropriate to report the MH OR. Instead report the Crude OR

c

Effect measure modification is present therefore it is not appropriate to report the MH OR. Instead report the stratified ORs

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