The codon change (Gly-12 to Val-12) in human H-ras that converts it to oncogenic H-ras has been
Question:
The codon change (Gly-12 to Val-12) in human H-ras that converts it to oncogenic H-ras has been associated with many types of cancers. For this reason, researchers would like to develop drugs to inhibit oncogenic H-ras. Based on your understanding of the Ras protein, what types of drugs might you develop? In other words, what would be the structure of the drugs, and how would they inhibit Ras protein? How would you test the efficacy of the drugs?
What might be some side effects?
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To develop drugs to inhibit oncogenic Hras its important to understand the structure and function of the Ras protein Ras proteins are small GTPases that play a crucial role in cell signaling pathways ...View the full answer
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