Question: The CRISPR-Cas system has been modified so that it can be used as a gene editing tool (look ahead to Figure 20.13). Describe how that

The CRISPR-Cas system has been modified so that it can be used as a gene editing tool (look ahead to Figure 20.13). Describe how that tool works, and explain how the natural CRISPR-Cas system is altered to produce it.

Figure 20.13

'3' tracrRNA 5' Spacer region, complementary Repeat to target gene crRNA (a)

Structure of an sgRNA Linker

'3' tracrRNA 5' Spacer region, complementary Repeat to target gene crRNA (a) Structure of an sgRNA Linker

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