The following table lists the intracellular osmolality concentrations of four osmoconforming organisms that are known to mimic the osmotic conditions of their surroundings.

Which of the following would likely have the largest direct effect on data in the table?
(A) A mutation in a cytoskeleton protein
(B) A mutation in a protein in the sodium-potassium pump complex
(C) A mutation in a lipid in the outer chloroplast membrane
(D) A mutation in a nuclear pore channel protein

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Table 1. Osmolality concentrations of osmoconforming organisms Organism 1 100 m0sm kg-¹ Organism 2 400 m0sm kg-¹ Organism 3 500 mOsm kg-¹ Organism 4 150 m0sm kg¹ Organism 5 350 m0sm kg-¹