The steady-state kinetics of an enzyme are studied in the absence and presence of an inhibitor (inhibitor A). The initial rate is given as a function of substrate concentration in the following table:

a. What kind of inhibition (competitive, uncompetitive, or mixed) is involved?
b. Determine Vmax and KM in the absence and presence of inhibitor.

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v[(mmol/L)min ] S (mmol/L) No inhibior InhibitorA 1.25 1.67 2.50 5.00 10.00 1.72 2.04 2.63 3.33 4.17 0.98 1.17 1.47 1.96 2.38