Question: Why is acyclovir converted to a nucleotide analog only in cells infected with herpes simplex virus?

Why is acyclovir converted to a nucleotide analog only in cells infected with herpes simplex virus?

Step by Step Solution

★★★★★

3.44 Rating (170 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock

Only the virus encodes the enzyme that catalyzes t... View full answer

blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Document Format (1 attachment)

Word file Icon

823-M-S-B-M-B (1210).docx

120 KBs Word File

Students Have Also Explored These Related Biology Questions!

Q:

A study was conducted with derivatives of the DNA nucleotide bases adenine and thymine bound inside micelles (Box 25-1) in aqueous solution. Sodium dodecyl sulfate forms micelles with the hydrocarbon...

Q:

(a) The 5`-nucleotide of inosine, inosinic acid (C10H13N4O8P), is added to foods as a flavor enhancer. What is the structure of inosinic acid? (The structure of inosine is given in Problem 27.38.)...

Q:

Consider the structures of arabinose and ri-bose. Explain why nucleotide derivatives of arabinose, such as ara-C and ara-A, are effective metabolic poisons. CHO HCOH CHO HOCH HCOH CH OH CH,OH...

Q:

Most humans are infected with herpes simplex virus-1 (HSV-1), the causative agent of cold sores. The HSV-1 genome comprises about I 00 genes, most of which are expressed in infected host cells at the...

Q:

2 5 Multiple Choice 3 points Certain viruses, like herpes simplex virus ( HSV ) , encode proteins that inhibit TAP transporters. How does this affect immune evasion? It prevents antibody - mediated...

Q:

You are charged with designing an occupational health and safety compliance training program for generic company--see Dyson article copied below: Choose a company in any of the following industries:...

Q:

. The thymidine analog 3 ' - azidothymidine ( AZT ) blocks replication of human immunodeficiency virus ( HIV ) . AZT is converted in cells to the 5 ' - triphosphate nucleotide derivative and then...

Q:

6-Mercaptopurine (Box 23-2), after its conversion to the corresponding nucleotide through salvage reactions, is a potent competitive inhibitor of IMP in the pathways for AMP and GMP biosynthesis. It...

Q:

The antiviral drug Acyclovir has an elimination half-life (t1/2,elim) of 2.5 hr and a volume of distribution (V) of 0.8 L/Kg. Estimate the following information for a 70 Kg patient that receives a...

Q:

Compute the amount of medication using the Ratio-Proportion Method to obtain your answer. Order: methylprednisolone acetate 100 mg IM once per week. Supply: methylprednisolone acetate 80 mg/mL...

Q:

Complete the following reactions. No explanation needed. MgBr I Et20 2. Haot HID4 Socla , Pyr oH 1TSCI, Pyr 2. NaSCHy

Q:

A businesses has just paid an annual dividend of $5.98. If you expected a constant growth rate of 8%, and have required rate of return of 12.65%, what is the current stock price according to the...

Q:

EXERCISE 2-1. Group Assignment Consider three very similar companies. Company A allocates manufacturing overhead to jobs using labor hours as the allocation base; Company B allocates manufacturing...

Q:

A project manager tries to motivate team members by focusing on job satisfaction, good working conditions, and maintaining positive relationships. Which theory is the project manager applying? a)...

Q:

A constitutive mutant is a strain that continuously makes a protein that is inducible in the wild type. Describe two ways in which a change in a DNA molecule could lead to the emergence of a...

Q:

Although a large number of mutagenic chemicals are known, none is known that induces mutations in only a single gene (gene-specific mutagenesis). From what you know about mutagens, explain why it is...

Q:

Why is it difficult in a single experiment to transfer a large number of genes to a recipient cell using transformation or transduction?

Q:

1. Portfolio Returns 10 Points A portfolio manager has made an investment that will generate returns that are subject to the state of the economy during the year. Use the following information to...

Q:

Please solve this in r software on the basis of Pima Dataset. In the `MASS` library, combine the two datasets `Pima.te` and `Pima.tr` back into one complete dataset, call it `pima`. (Try function...

Q:

Nancy Howe, your staff assistant on the April 30, 20X2, audit of Wilcox Company, was transferred to another audit engagement before she could complete the audit of unrecorded accounts payable. Her...