Question: Write a balanced chemical equation for the pentose phosphate pathway in the first two modes depicted in Figure 12.36, where (a) ribose-5-phosphate synthesis is maximized
(a) ribose-5-phosphate synthesis is maximized
(b) NADPH production is maximized, by con- version of the sugar phosphate products to glucose-6-phosphate for repeated operations of the pathway.
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CEP G6P CXIDATIVE PHASE NADP 2 NADP NADH CO2 SPa 6PG Ru5 P (NADP NAD F6P GAP co RuSP RusP FBP Gycolysis NONOXIDATIVE PHASE RS P aAP 2 ATP Nucleotides 002 a) Nucleotide ayntheaia When the primary need is ior nuclaotide biosynmhesis,1he primary produci is ribose--phosphata. DHAPFBP Chric cycle b)NADPHayntheeia. When the primary need is or reducing pover (NADPH), ruclose phcsphates sle reconverded 1o glucose-e-phos phete tor ecxidation in thecidslive phese FADH NADH ABBREVIATIONS GeP -glucose-e-phosphata R5P-ritose-s-phosphate (b) Energy generatian. F6P-ucose-e-phosphate DHAP dihydroxyacelone phosphate FBP-ructse-1e-bisphosphsle Whanonly moderate quanties pentose hosphales and NA DP H are needed. 1 he pathveycan also be usad to supply energy withthe resclion producis being oxidized thiro ugh ghycolysi snd1he ciric acidcycla
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