Question: A sample of a circular plasmid is digested with Type IA topoisomerase and analyzed by agarose gel electrophoresis followed by staining with ethidium bromide. Fifteen

A sample of a circular plasmid is digested with Type IA topoisomerase and analyzed by agarose gel electrophoresis followed by staining with ethidium bromide. Fifteen bands of DNA are visible. What do these bands represent and how do their linking numbers differ?

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