Question: In Chapter 11, a continuous cascaded compensator for a unity feedback system was designed for the treatment of the HIV-infected patient treated with RTIs (Craig,

In Chapter 11, a continuous cascaded compensator for a unity feedback system was designed for the treatment of the HIV-infected patient treated with RTIs (Craig, 2004). The transfer function of the designed compensator was

-2 x 10-4(s2 +0.04s + 0.0048) s(s +0.02) Ge(s) = %3D

The linearized plant was given by

The compensated system is overdamped with an approximate settling time of 100 seconds. This system must be discretized for practical reasons: (1) HIV patient cannot be monitored continuously and (2) medicine dosage cannot be adjusted continuously.

a. Show that a reasonable sampling period for this system is T = 8 days (medicine dosage will be updated on a weekly basis).

b. Use Tustin’s method and T = 8 days to find a discrete equivalent to Gc(s).

c. Use Simulink to simulate the continuous and discrete compensated systems for a unit step input. Plot both responses on the same graph.

-2 x 10-4(s2 +0.04s + 0.0048) s(s +0.02) Ge(s) = %3D

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