What hypothesis test can be used to test the hypothesis that the percentage of abnormal FEV values

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What hypothesis test can be used to test the hypothesis that the percentage of abnormal FEV values among exposed men differs from the general-population estimates? 


Environmental Health, Pulmonary Disease

A clinical epidemiologic study was conducted to determine the long-term health effects of workplace exposure to the process of manufacturing the herbicide (2,4,5 trichlorophenoxy) acetic acid (2,4,5-T), which contains the contaminant dioxin [7]. This study was conducted among active and retired workers of a Nitro, West Virginia, plant who were exposed to the 2,4,5-T process between 1948 and 1969. It is well known that workers exposed to 2,4,5-T have high rates of chloracne (a generalized acneiform eruption). Less well known are other potential effects of 2,4,5-T exposure. One of the variables studied was pulmonary function.


Suppose the researchers expect from general population estimates that 5% of workers have an abnormal forced expiratory volume (FEV); defined as less than 80% of predicted, based on their age and height. They found that 32 of 203men who were exposed to 2,4,5-T while working at the plant had an abnormal FEV.

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