What is the sensitivity of this test?

To possibly improve on the diagnostic accuracy of the clinical diagnosis for Alzheimer€™s disease, information on both the APOE genotype as well as the clinical diagnosis were considered. The data are presented in Table 3.16.

Table 3.16: Influence of the APOE genotype in diagnosing Alzheimer€™s disease (AD)

Suppose we consider the combination of both a clinical diagnosis for Alzheimer€™s disease and the presence of ‰¥ 1 ε4 allele as a screening test for Alzheimer€™s disease.

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Both clinical and pathological criteria for AD Only clinical criteria for AD Only pathological criteria for AD Neither clinical nor pathological criteria for AD APOE genotype 1076 21 e4 allele No ɛ4 allele 66 66 67 567 124 61 161 1643 190 127 228 Total