Indomethacin (an anti-inflammatory drug, MW=357.79) is to be delivered by a surgically implanted drug-delivery device in which

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Indomethacin (an anti-inflammatory drug, MW=357.79) is to be delivered by a surgically implanted drug-delivery device in which the drug inside a membrane reservoir transfers through the membrane to the surrounding fluid and tissue. The outside surface area of the reservoir is 3.5 cm2. Furthermore, the concentration of the drug on the outside surface of the reservoir is 5.8 × 10−5 gmol/L, but the concentration a few centimeters from the reservoir can be assumed to equal 0. The fluid outside the reservoir is flowing slowly, which aids the transfer, and the mass-transfer coefficient is 0.016 cm/s. How much time will be required to deliver 50 mg of the drug?

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