Imidazole is a common molecular species in biological chemistry. For example, it constitutes the side chain of

Question:

Imidazole is a common molecular species in biological chemistry. For example, it constitutes the side chain of the amino acid histidine. The rate constant for the protonation reaction is 5.5 × 1010 M–1 s–1. Assuming that the reaction is diffusion controlled, estimate the diffusion coefficient of imidazole when D(H+) = 9.31 × 10–5 cm2 s–1, r(H+) ~ 1.0 Å, and r(imidazole) = 6 Å.Use this information to predict the rate of deprotonation of imidazole by OH (D = 5.30 × 10–5 cm2 s–1 and r = ~1.5 Å).

Fantastic news! We've Found the answer you've been seeking!

Step by Step Answer:

Related Book For  book-img-for-question

Physical Chemistry

ISBN: 978-0321812001

3rd edition

Authors: Thomas Engel, Philip Reid

Question Posted: