Question: A semi - batch bio - reactor with the volumetric flowrates Fi ( in liters / hour ) for the inlet stream, has an initial

A semi-batch bio-reactor with the volumetric flowrates Fi (in liters/hour) for the inlet stream, has an initial liquid volume V =2 L for the contents inside, which is changing since there is only Fi. Assume that the density of all material is constant at =1 g/L. There are no cells or product in the inlet stream. The reactor is well mixed. Substrate is present in the inlet stream. The inlet concentration of substrate is Sf =10 g/L (constant). Take the concentrations of substrate, cells and products inside the reactor as S, X and P, all varying with time (all in g/L). The growth rate of the cells and products is defined as:r_g=X where the specific growth rate () of the cells is given by (_m S)/(K_S+S) with maximum specific growth rate (_m) as 0.1 h-1 and KS =2 g/L. r_P=Y_(P/X)*r_g where Y_(P/X)=0.1. Also, take Y_(X/S) and Y_(P/S) both as 0.2. Fi can be taken as 1 L/h and the steady state values of X, S and P can all be taken as 2 g/L. Derive a model for the reactor by doing the overall MB and component balances for the cell, substrate and products. Remember that the only variables in the system are V, X, P and S.

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