Consider the following haploid Wright-Fisher populations: [10] a. What is the chance of fixation and the chance
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Question:
Consider the following haploid Wright-Fisher populations: [10]
a. What is the chance of fixation and the chance of loss of the A1 allele after one generation of drift, where:
i. f_(A_1 ) = 0.75, N = 10 [2]
ii. f_(A_1 ) = 0.75, N = 1000 [2]
iii. Where A1 is a new mutation and N = 10 [2]
iv. Where A1 is a new mutation and N = 100 [2]
b. The chance that a new mutation is lost due to drift converges on Pr(X = 0) = e-1 with increasing N. Confirm this by comparing this value with the chance of loss of a single-copy allele in haploid populations where N = 100, 500, 2000 and 10000 [2].
Related Book For
Probability and Statistics
ISBN: 978-0321500465
4th edition
Authors: Morris H. DeGroot, Mark J. Schervish
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