Question: For this part, ( a ) determine how long will it take for the fluid to travel along the channel having dimensions and then (
For this part, a determine how long will it take for the fluid to travel along the channel having dimensions and then b through a first porous paper layer of the test strip. Typical microfluidic channel dimensions in a glucometer of rectangular shape are: a width of approximately a thickness on the order of and lengths of a few millimeters. For the first layer of the test strip, a common material used in lateral flow assays Whatman Qualitative filter paper, Grade
As discussed in today's prototype lab session, one approach to assess transport time for these segments, is to use the Washburn expressions given below. For sample volumes ranging from i to ii to iii please determine the time it will take for each of the sample sizes to reach the amperometric transduction subfunction.
Time to fill the sample chamber can be modeled by the Washburn equation which can be modified to describe capillary flow between two parallel plates:
where
filling time
viscosity
channel length along fill axis
liquid surface tension
contact wetting angle and...
s capillary thickness channel height
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