A patient comes into the emergency department with a serious condition that needs to be addressed immediately
Question:
A patient comes into the emergency department with a serious condition that needs to be addressed immediately with drug A. The effective & safe concentration for drug A is 7 mg/L. Its clearance is ~0.03L/hr, and its t 1⁄2 is 2 days. The drug's volume of distribution is 2 L. Which of the following is the best course of treatment?
(A) Start giving the medication in a maintenance dose po and let it go to steady state by 4-5 x t 1⁄2
(B) Start with an IV loading dose of 7 microgram and continue with an appropriate maintenance dose.
(C) Start with an IV loading dose of 3.5 milligram and continue with an appropriate maintenance dose.
(D) Start with an IV loading dose of 14 milligram and continue with an appropriate maintenance dose.
(E) Give a one time IV dose of 280 milligram so that the patient will be covered for a long time.
Financial Accounting
ISBN: 978-0077862268
2nd edition
Authors: J. David Spiceland, Wayne Thomas, Don Herrmann