The reaction below is a direct enolate alkylation. It has been found that this reaction only works well with unhindered methyl and 1 alkyl halides. Pick the statement that best explains this observation. 1. LDA, THF, -78C 2. CHBr Br The nucleophilic enolate requires a reaction center that has a positive charge. Hindered alkyl halides do not undergo SN1 reactions. O Hindered alkyl halides do not undergo SN2 reactions. O Methyl and 1 alkyl halides can form carbocations that can readily react with the nucleophilic enolate

Answer rating: 100% (QA)

The reaction you describe is an example of an enolate alkylation This involves a nucleophilic attack ... View the full answer