In the experiment of Figure 7.1, Lederberg and Tatum could not discern whether met+ bio+ genetic material

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In the experiment of Figure 7.1, Lederberg and Tatum could not discern whether met+ bio+ genetic material was transferred to the met− bio− thr+ leu+ thi+ strain or if thr+ leu+ thi+ genetic material was transferred to the met+ bio+ thr− leu− thi− strain. Let’s suppose that one strain is streptomycin-resistant (say, met+ bio+ thr− leu−thi−) and the other strain is sensitive to streptomycin. Describe an experiment that could determine whether the met+ bio+ genetic material was transferred to the met − bio− thr+ leu+ thi+ strain or the thr+ leu+ thi+ genetic material was transferred to the met+ bio+

thr− leu− thi− strain.

Figure 7.1

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