Question: Would the following alterations to Src be oncogenic? Explain. (a) The mutation of Tyr 527 to Phe. (b) The replacement of Src residues 249 to
(a) The mutation of Tyr 527 to Phe.
(b) The replacement of Src residues 249 to 253 with the sequence APTMP.
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a Yes because the phosphorylation of Tyr 527 is required for the autoinhibition of S... View full answer
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