Smith (1969, Section 21 10) quotes an example on genetic linkage in which we have observations x (x 1 , x 2 , x 3 , x 4 ) with cell probabilities The values quoted are x 1 461, x 2 130, x 3 161 and X 4 515 Divide x 1 into Yo and Y 1 and X 4 into y 4 and Y 5 to produce augmented data y (y 0 , Y 1 , Y 2 , y 3 , Y 4 , Y 5 ) and use the EM algorithm to estimate n ( n, n ( n), (1 n) k)

Question: Smith (1969, Section 21.10) quotes an example on genetic linkage in which we have observations x = (x 1 , x 2 , x 3

Smith (1969, Section 21.10) quotes an example on genetic linkage in which we have observations x = (x₁, x₂ , x₃ , x₄) with cell probabilities

( +n, n ;( n), (1 n)+k). The values quoted are x₁ = 461, x₂ = 130, x₃= 161 and X₄ = 515. Divide x₁ into Yo and Y₁ and X₄ into y₄ and Y₅ to produce augmented data y = (y₀, Y₁, Y₂, y₃, Y₄, Y₅) and use the EM algorithm to estimate n.

( +n, n ;( n), (1 n)+k).

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