# Smith (1969, Section 21.10) quotes an example on genetic linkage in which we have observations x =

## Question:

Smith (1969, Section 21.10) quotes an example on genetic linkage in which we have observations x = (x_{1}, x_{2} , x_{3} , x_{4}) with cell probabilities

The values quoted are x_{1} = 461, x_{2} = 130, x_{3 }= 161 and X_{4} = 515. Divide x_{1} into Yo and Y_{1} and X_{4} into y_{4} and Y_{5} to produce augmented data y = (y_{0}, Y_{1}, Y_{2}, y_{3}, Y_{4}, Y_{5}) and use the EM algorithm to estimate n.

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