Consider the formation of double-stranded (DS) DNA from two complementary single strands (S and S²) through the

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Consider the formation of double-stranded (DS) DNA from two complementary single strands (S and S€²) through the following mechanism involving an intermediate helix (IH):

S+S=H →DS н-

a. Derive the rate law expression for this reaction employing the preequilibrium approximation.

b. What is the corresponding rate law expression for the reaction employing the steady-state approximation for the intermediate IH?

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Physical Chemistry

ISBN: 978-0321812001

3rd edition

Authors: Thomas Engel, Philip Reid

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