RASSF1A is a tumor suppressor gene that is expressed in normal liver cells Its protein expression is either undetectable or greatly reduced in most liver tumor biopsies However, DNA sequencing showed that the RASSF1A gene locus including the promoter and the exons have no mutations Based on what you have learned, what could be the underlying mechanisms (list at least five different mechanisms with some explanations)

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RASassociation domain family 1 A RASSF1A is an effector of Ras oncogene This gene is present on chromosome 3p213 and is nearly an 11 kb region with ei... View the full answer