The likelihood of any particular base in a given position is 1/4 (because there are 4 types
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The likelihood of any particular base in a given position is 1/4 (because there are 4 types of bases) and the likelihood of a purine is 1/2. If you assume random base arrangements, the likelihood of the six-base sequence is (1/4)(1/4) (1/2)(1/4)(1/4)(1/4), which equals 1/2048. In other words, this sequence would occur every 2048 bp by random chance alone.
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