The base analog 5-bromouracil (5BU), Which sterically resembles thymine, more readily undergoes tautomerization from its keto form
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Which sterically resembles thymine, more readily undergoes tautomerization from its keto form to its enol form than does thymine. 5BU can be incorporated into newly synthesized DNA when it pairs with adenine on the template strand. However, the enol form of 5BU can pair with guanine rather than adenine.
(a) Draw the 5BU G base pair.
(b) What type of mutation results?
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Related Book For
Fundamentals of biochemistry Life at the Molecular Level
ISBN: 978-0470547847
4th edition
Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt
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